You can upload CSV file with a single email column to bulk add/remove contacts from a list.
Go to contact lists page. Select list and click Upload CSV.
Specify if you want to Add Contacts or Remove Contacts. Attach CSV file with single email column and click Upload.
Keep in mind that CSV upload will only add/remove existing contacts from list. It will not create new contacts and will skip suppressed contacts.
Using Bulk Actions
Another way to bulk add/remove contacts from list is to use bulk actions.